Review argues for therapeutics to treat cholesterol cousins called ceramides

Therapeutics that target lipids called ceramides might hold potential for treating cardiometabolic disease, argues a review article published November 5th in the journal Trends in Pharmacological Sciences. The authors summarize evidence supporting a strong relationship between ceramides and a range of diseases in animals and humans and compare it to the decades of datasets that […]

Researchers detect a diffusion barrier inside fly brain

The neurons, located in the brain are interconnected in a complex pattern and establish special communication points, the synapses. All neurons require a constant environment in order to function reliably. To ensure this, the brain is surrounded by the so-called blood-brain barrier. It ensures, for example, that the nutrient balance always remains the same and […]

How doctors can help their patients make heart-healthy lifestyle changes

Lifestyle change is a powerful, proven way for a person to prevent heart disease. But to make healthy changes stick, people often need a little help. Primary care doctors could offer crucial assistance in connecting patients with counseling that’s been shown to make a difference. But because of time constraints or other barriers, those doctors […]